Vietnam is a long way from the United States, and the flight is the part of the trip most people underestimate. The headline numbers matter less than two structural facts: there is only one nonstop, and the arrival date on your ticket is almost never the day you left.
The nonstop options, and who they serve
Vietnam Airlines flies nonstop from San Francisco to Ho Chi Minh City, at roughly sixteen to seventeen hours westbound. That single route is the entire nonstop map between the United States and Vietnam. If you are starting from the West Coast and your trip begins in the south, this is the simplest way to do it.
From anywhere else — New York, Newark, Washington, Chicago, Dallas, Seattle — you will connect at least once. There is no nonstop to Hanoi from the United States at all, which is worth knowing before you plan a north-to-south route.
Where you connect, and why it matters
The realistic hubs are Seoul Incheon, Tokyo Narita or Haneda, Taipei, Hong Kong, Singapore, and the Gulf airports at Doha and Dubai. North Asian hubs are usually the shortest total routing from the East Coast and the West. Gulf routings are often cheaper and almost always longer, sometimes adding six or more hours of total journey.
Door to door, plan on twenty-two to twenty-six hours from the East Coast with one stop. That total elapsed figure is the number to plan around, not the flight time, because it determines what state you arrive in and whether the first day of your itinerary is real.
Where the nonstop lands, and where it does not: Ho Chi Minh City · Hanoi. (Enable JavaScript for the interactive map.)
The calendar day you lose
Vietnam has a single time zone and does not observe daylight saving, so the gap to the United States shifts by an hour twice a year rather than staying fixed — twelve hours ahead of the East Coast during Eastern Standard Time, eleven during Eastern Daylight Time. Combined with the westbound flight time, a departure on Monday evening typically lands on Wednesday morning. You lose a calendar day going out and nominally gain it coming back.
The practical consequence is that two weeks on the ground is not two weeks away from home: the outbound crossing eats a calendar day and the return takes most of another, so count the travel days separately when you work out how much leave you need. Build the arrival day in as a write-off rather than scheduling anything into it.
Which city to fly into
The default assumption is to fly into one end and out of the other, which avoids backtracking the length of the country. Open-jaw tickets into Hanoi and out of Ho Chi Minh City, or the reverse, are widely available and usually cost little or nothing more than a return.
If the nonstop from the West Coast is what makes the trip affordable, that points you to starting in Ho Chi Minh City and travelling north. If you are connecting anyway, the direction is open and should be decided on other grounds — season, Tet, and what you want to see first.
Da Nang as a third option
Da Nang now has a reasonable number of international connections through the Asian hubs and sits in the middle of the country. For a trip focused on the central coast — Hoi An, Hue, the beaches — flying in and out of Da Nang removes two internal legs that would otherwise eat a day each.